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Early symptoms of Parkinsons disease include: A slight tremor in one hand Shrinking handwriting Reduced sense of smell Sleep disrupted with night terrors and violent thrashing Reduced balance Stiffness when moving or walking Chronic constipation Mask of Parkinsons marked by staring and loss of emotional facial expression As the disease advances, symptoms become increasingly severe and unmanageable, and loved ones are often faced with difficult decisions for long-term care

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In 2023, the FDA classified BPC-157 as a Category 2 bulk drug substance, restricting its use by compounding pharmacies

doi: 10.3390/ijms21124370

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