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Vitamin B12, the most complex of vitamins, is only synthesized by bacteria and archaea

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Sulforaphane promotes immune responses in a WEHI-3-induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo

This is particularly important for cells of the immune system, such as monocytes/macrophages to maintain a continuous defence against microorganisms

Thus, in an antidoping context, one may define brain doping as the use of substances or methods to enhance performance by directly or indirectly modulating cognitive capacities, brain activity, or function [9]