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The loading dose was 150 mg/kg followed by a maintenance dose of 50 mg/kg over 4 hours and then 100 mg/kg over 16 hours

Experimental studies indicate that supraphysiological testosterone exposure increases reactive oxygen species generation within cardiomyocytes while reducing the activity of endogenous antioxidant enzymes, including superoxide dismutase and glutathione peroxidase (72)

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This includes fragmented DNA, reduced motility, and impaired mitochondrial function, all of which hinder fertility potential

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