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Its Olink Explore HT platform covers approximately 5,400 protein targets and is based on proximity extension assay (PEA) technology (Olink, 2024)

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One report showed that neutrophils have minimal effects on BDL-induced liver fibrogenesis, as there is no significant difference in the production and deposition of collagen in the livers of anti-neutrophil antiserum treated mice or mice with neutrophil dysfunction due to transgenic expression of IL-8 (90)

While p53 modulators, including FOXO4-DRI, MDM2 inhibitors, and USP7 inhibitors have shown senolytic effects by selectively eliminating senescent cells or promoting their apoptosis in the laboratory, translating these findings to the clinic have so far been unsuccessful

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