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Description
Trends Immunol (2007) 28:14
GSH is not just a good biological antioxidant because of its reaction rate with HOCl which is generated during inflammations by myeloperoxidase but rather because the higher oxidation products generated are effective antioxidants
Clinical and Experimental Pharmacology and Physiology 42: 617621
When exposed to oxidizing stimuli, KEAP1s cysteine residues are bound by ROS, changing the proteins structure
Therefore, the upregulation of catabolic pathways and the expression of cyst(e)ine transporters is often observed in cancer together with the upregulation of cysteine synthesis
Molecular knots in biology and chemistry
