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Updated November 2024
observed TP53 mutations in 10/55 (18%) patients with low and intermediate-1 risk MDS carrying del(5q), which render them at higher risk for disease evolution to AML [527] Another investigation reported TP53 mutations in 17% of lower-risk MDS with isolated del(5q),associated with shorter survival [554]

Selkrig et al., 2018), and it has no effect on circadian timing of locomotor behavior (Silva et al., 2021)
