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Subunits from each of the four septin subgroups assemble into hetero-oligomeric complexes in a specific order, including hexamers (SEPT2SEPT6SEPT7SEPT7SEPT6SEPT2) and octamers (SEPT2SEPT6SEPT7SEPT9SEPT9SEPT7SEPT6SEPT2), with alternating G-interface (consisting of the GTP-binding domain) and NC-interface (comprising the amino- and carboxy-terminal regions) along the linear hetero-oligomeric complex 8,11

Use sterile supplies and sanitize vial stoppers

Coordination of erythropoiesis by the transcription factor c-Myb

doi: 10.3945/an.112.002154

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Determined the highest non-severely toxic dose (HNSTD) to be 10 mg/kg based on pulmonary findings