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ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ERmitochondria contact sites

doi: 10.1016/j.ebiom.2022.104163 109 LiH.ZhangL.LiJ.WuQ.QianL.HeJ.et al

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Our results showed a specificity of changes in L1CAM exosomes but not in total circulating exosomes in subjects with MDD
These multidimensional factors spanning mitochondrial metabolism, cellular aging, metabolic function, and childhood trauma provided more detailed signatures to predict longitudinal changes in depression severity than each individual factor alone