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Demyelination: The role of reactive oxygen and nitrogen species

the arithmetic difference between two ion signals, in this case m / z 539 and 306) and an analogue of glutathione (fragment ion at m / z 272)

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Early studies have found that the brains of people with PD, AD, MS and mild cognitive impairment (MCI), exhibit high levels of oxidative damage, including mitochondrial dysfunction, DNA and protein damage, lipid peroxidation, and myelin injury [62, 63]

PMID: 27083250

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