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Tsujimaru et al

Next, enucleated cell cytoplasts from this mtDNA 4696-nt deletion cell line were fused to single-cell mouse embryos, the embryos implanted into foster mothers, and the resulting mice found to be heteroplasmic for the deleted mtDNA

Tumor microenvironment remodeling Tumor cells reside in a highly heterogeneous niche composing of extracellular matrix and stromal cells such as fibroblasts, macrophages, and endothelial cells
this is usually associated with another disease such as a collagen vascular disease (e.g., rheumatoid arthritis, severe systemic lupus erythematosus) or drugs, or it is idiopathic

doi: 10.1158/2326-6066.CIR-13-0150 52 NemethZLiMCsizmadiaEDmeBJohanssonMPerssonJLet al

Myokymia of pharyngeal and laryngeal muscles increases the risk of pulmonary aspiration
