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& Hasnain, S
In a randomised, double-blind, controlled trial of 400 mg/day of hydroxychloroquine versus placebo in patients with asymptomatic HIV infection and not on anti-retroviral therapy, hydroxychloroquine was found to be associated with an increased HIV viral RNA load as well as a faster decline in CD4 + cell counts, leading to the need to initiate anti-retroviral therapy [87]
These findings are based on CRISPR deletions of glucose-6-phosphate dehydrogenase (G6PD, the committed oxPPP enzyme), ME1, IDH1 and combinations thereof in HCT116 colon cancer cells
Xiang X, Liu Y, Zhang X, Zhang W, Wang Z
AfA: Data curation, Formal Analysis, Methodology, Software, Validation, Visualization, Writingoriginal draft, Writingreview and editing
Johnstone TB, Gu Z, Yoshimura RF, Villegier AS, Hogenkamp DJ, Whittemore ER, et al
