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Similarly, in acute liver failure, the activation of SIRT1 induces the acetylation of p53, thereby inhibiting the p53/GPX4/GSDMD axis and alleviating damage caused by ferroptosis [12]

Modified cytosines (5-fC or 5-caC) are recognized and excised by thymine DNA glycosylase (TDG), a key enzyme belonging to base excision repair (BER) machinery

The Nrf2/Ho-1 Axis in cancer cell growth and chemoresistance

By supporting the structural integrity of the liver, milk thistle ensures the "machinery" responsible for glutathione production is in top shape

To further verify the 4D-label-free proteomics results, we selected proteins related to oxalate degradation, methane synthesis, and antioxidant mechanisms for Parallel Reaction Monitoring (PRM) validation of key differential proteins

This allows for increased sputum clearance due to reduced viscosity