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Lv DD, Wang YJ, Wang ML, et al

Attia et al

The present review examines the multifarious functions of TMAO and betaine with possible molecular mechanisms towards a better understanding of their emerging and diverging functions with probable implications in the prevention, diagnosis, and treatment of human diseases

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However, chemical inhibition of lactate production via LDH inhibitors diminishes Treg cell function in the TME by suppressing MOESIN Kla, ultimately enhancing the HCC response to anti-PD-1 treatment

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