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[4] The researchers posited that ARA-290 protected islets from cytokine-induced damage and apoptosis
Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment
10.1016/j.cmet.2011.08.014 164 YouA.LiY.ShenC.FanH.HeJ.LiuZ.et al (2023)
26 Given the burgeoning interest in copper metabolism and cuproptosis, it is crucial to develop a comprehensive understanding of the molecular mechanism and therapeutic landscape of copper and cuproptosis in cancer
Cellular energy strategies work better when core nutrient status is not neglected
ROS trigger apoptosis by activating the pro-apoptotic proteins caspase-3/7/9 and cleaved PARP, disrupting mitochondrial function, and in pancreatic cancer melatonin-induced ROS enhance apoptosis through the mitochondrial pathway (Florido et al., 2022b)
