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10.1056/NEJMoa1506348 42

A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 g per day per os (p.o.) for 8 weeks (form not reported)

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In contrast, Ruminococcaceae UCG-009 was present in all experimental groups, and exhibited significantly greater relative abundance in both the LD control group and the 5A-1MQ-treated group switched from WD to LD compared to the WD control group (both significant before FDR correction