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A comprehensive evaluation of these supplements within evidence-based frameworks is essential to guide their safe and effective integration into clinical practice

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Caruso 2013

Grxs catalyze glutathionylation, post-transcriptional modifications, and the disulfide exchange between GSSG and protein thiols (PrSH) [139] (Figure 3)

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In primary neurons, endogenously synthesized -glutamylcysteine fully prevents apoptotic death in several neurotoxic paradigms and, in an in vivo mouse model of neurodegeneration, -glutamylcysteine protects against neuronal loss and motor impairment