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Functional modifications, such as chloroquine, histidine, PEG, or PEI, have been incorporated into PLL to address these limitations

As TNF alpha is tumor-promoting [96, 97], the estrogen-mediated repression of TNF alpha may support a stronger anti-tumor immune microenvironment in bladder tumors of patients with female gonads

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a form of D-ribose, a naturally occurring sugar molecule

European Association for Study of Liver, 2012), although it should be noted that disease-causing mutations have been found to have variable penetrance (Bandmann et al., 2015)

neoformans secretes extracellular urease to modulate phagosomal pH, which in turn promotes the conditions necessary for melanization, persistence in phagocytic cells, and eventual traversal of the blood-brain barrier 34