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Families matter: social support and mental health trajectories among lesbian, gay, bisexual, and transgender youth

It is well known that in areas with severe and chronic iodine insufficiency, hypothyroidism can occur in both mothers and fetuses from the early stages of gestation, leading to irreversible brain damage, mental retardation, and neurological abnormalities [11,12]

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Subsequently, the study found that reducing the plasma LEAP2/ghrelin ratio reversed cognitive deficits in aged mice by restoring hippocampal neurogenesis, alleviating synaptic loss, and inhibiting neuroinflammation