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The classic M1/M2 paradigm is insufficient to describe their phenotypic continuum, making corresponding metabolic states highly dynamic and difficult to target predictably

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After SCI, rats were given curcumin at a dosage of 110 mg/kg body mass per day for 2 weeks

Eye involvement: Itchy, watery eyes strongly suggest histamine response rather than infection

[DOI] [PubMed] [Google Scholar] 38.Abbott, C

These findings highlight how exosomal cargo can regulate key inflammatory pathways to drive anti-inflammatory polarization, offering a promising therapeutic strategy for spinal cord repair, as detailed in Table 8