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La NIQ deteriora la funcionalidad, compromete la calidad de vida y, frecuentemente, conlleva la reduccin y/o suspensin del tratamiento, lo que representa un efecto adverso limitante de dosis de muchos antineoplsicos

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Access this article Similar content being viewed by others References Aguilar MA, Minarro J, Felipo V (2000) Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats

Moreover, in the NH 4 Cl-treated human astrocytes, increased concentration of 3-methyl-2-oxovaleric acid, which was ammonia induced and played a crucial role in neurological impairment, was significantly decreased with l-carnitine co-treatment
