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During pregnancy, breastfeeding, kidney failure, or with a history of epilepsy, supplementation should only be used under medical supervision

A review of several clinical and case studies of people who use Melanotan concluded that the side effects observed in clinical trials are largely minor [16]

Medical necessity required: Thorough documentation must justify deep sedation or general anesthesia, especially for low-risk or healthy individuals

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If nausea persists beyond 10 days at reduced dose, discontinue and consult a prescribing physician

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Collet T-H, Dubern B, Mokrosinski J