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Corroborating these findings, both FTH and FTL overexpression have also been implicated in chemotherapy resistance across various tumor types and chemotherapeutic agents (reviewed in ref
Qin Y, Bai D, Tang M, Zhang M, Zhao L, Li J, et al
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Accumulating evidence has verified that perturbation of Gln metabolism can significantly affect TCA cycle flux and tumor cell proliferation [48,49,50]
Herbert, 2005)
