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Interestingly, their effects on GH synthesis seem to be concentration-dependent, as low and high concentrations of nesfatins downregulate the expression of GH mRNA, while medium concentrations of nesfatins does not produce this effect (443)

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The co-expression of FOXP3 and glucocorticoid receptor (GR) was increased after TAT-GILZ treatment

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The fatty acid chain attachment and amino acid substitutions reduce degradation susceptibility