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When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established

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When B12 is lacking, your body produces oversized, dysfunctional red blood cells, leading to a condition called megaloblastic anemia

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Alcohol and Vitamin B12 Deficiency Effects Vitamin B12 is soluble in water and is stored in the body for timely use