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By sequestering actin monomers and controlling their polymerization into filaments, TB-500 enables enhanced migration of fibroblasts, endothelial cells, and immune cells to injury sites

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Phosphorylation at Ser167 promotes protein tetramerization, and at two other sites, it increases its enzymatic activity

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Majorly these compounds act as an antifungal phytoalexin, the compound which is synthesized in response to injury

C., et al., New Genetic Loci Link Adipose and Insulin Biology to Body Fat Distribution, Nature 518, no