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Mitochondria-targeting natural product rhein conjugated with dichloroacetate as the dual inhibitor of glycolysis and oxidative phosphorylation to off energize cancer cells and induce ROS storm

Seim H, Loster H, Claus R, Kleber HP, Strack E: Stimulation on the anaerobic growth of Salmonella typhimurium by reduction of L-carnitine, carnitine derivatives and structure-related trimethylammonium compounds

That said, the sample size of the existing studies has been very small, and research with larger sample sizes is required

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If supplementing, 250 mg per day is considered a reasonable dose [14]