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Under pathological conditions, ferroptosis causes intestinal epithelial damage, characterized by crypt disruption, a reduction in goblet cells, and degradation of tight junction proteins

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L'enzyme slnie glutathion-peroxydase est essentielle la dtoxication des oxydants de type peroxydes (eau oxygne, peroxynitrite), qu'ils soient d'origine exogne ou endogne (respiration cellulaire, peroxyde d'hydrogne form par d'autres processus antioxydants complmentaires, peroxynitrite impliqu dans l'apoptose cellulaire ou le systme immunitaire)

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The attribution of a specific effect to one of these hormones or to the GH/IGF-1 system is generally difficult to be established, as most of the data on the effects of GH and IGF-1 at the ovarian level come from cultured cells or studies in animals, and the effects seem to be different depending on the species

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Il est fabriqu par les cellules du foie et se situe particulirement dans les cellules rnales, cardiaques et au niveau du cerveau

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Bioavailability assays ensure optimum cellular uptake

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Glutathione S -transferase mediated the introduction of S -methyl or sulfhydryl (Niu et al

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