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heated lymphocyte extracts with or without 5-methyl THF and observed that MTHFR activity was greater in samples heated with folate supplementation, indicating a protective effect on MTHFR by folate [4]

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However, some studies, especially in vitro experiments, reported potentiation of harmful HM actions in the presence of EGCG

Patients with inflammatory bowel conditions, leaky gut, or NSAID-induced gastric damage have sought it as an adjunct or alternative therapy