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( B ) Heatmap of GSH pathway metabolites intensity normalized by row as a z score from A549shNRF2-BIND-luc cells treated with 1 M A-485 for 24 h

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Recently, CoA-thiolation (i.e., CoAlation) of proteins has been shown to occur as a reversible post-translational modification induced by oxidizing agents and metabolic stress conditions in S