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Additional factors include genetic variability in the glutathione S-transferase M1 gene that could affect the metabolism of SF (6)
This has been reported as a major resistance mechanism against cDDP in several types of cancer [64, 65] and is believed to justify cell death when repairs are not possible [66]
A schematic is shown in Figure 5F
Vithalkar MP, Pradhan S, Sandra KS, Bharath HB, Nayak Y (2025) Modulating NLRP3 inflammasomes in idiopathic pulmonary fibrosis: a comprehensive review on flavonoid-based interventions
Since sulfonium compounds are high-energy compounds, a -elimination reaction yielding THT and aminoacrylate should be energetically favorable
Teoh Bing Fei J, Yee A, Bin Habil MH, Danaee M
