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In addition, SLC7A11 was confirmed as a downstream target of FTO-demethylated m6A modification in PTC [95]

This pathway of xCT induction by neuronal activity was also prevalent in the hippocampi of epileptic patients, pointing to its potential role in epilepsy, probably via the upregulation of extracellular glutamate 41

Although polyribosomes also form in eukaryotes, they cannot do so until RNA synthesis is complete and the RNA molecule has been modified and transported out of the nucleus

In line with this phenotype, liver microarray analyses consistently show dramatic intrinsic suppression of lipogenic genes in GCLM KO mice 17,39

Ferroptosis nanomaterials are novel approaches for cancer treatment [78, 79]

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