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Development of appropriate therapeutic strategies to complement the assessment of sperm DNA damage is very much essential for the treatment of patients with male infertility as DNA damage in the male germ line is a major risk factor for adverse clinical outcomes including poor fertilization, impaired development of the pre-implantation embryo, miscarriage and an increased risk of morbidities and mortality in the offspring

In addition, this decline in aged people was also attributed to the loss of type II fibers [78]

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Nasca C, Dobbin J, Bigio B, Watson K, de Angelis P, Kautz M, Cochran A, Math AA, Kocsis JH, Lee FS, Murrough JW, McEwen BS, Rasgon N (2021) Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance

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