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Patients with active hematologic disorders, those currently on erythropoietin therapy, or anyone with contraindications identified during consultation should discuss alternative approaches with their provider

Nat Clin Pract Nephrol
Translating mechanisms into practical protocols Understanding biology helps optimizing clinical application

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However, in individuals with a confirmed or subclinical B12 deficiency, correcting that deficiency can lead to the following: Improved energy levels and reduced fatigue Better exercise tolerance and recovery More stable mood and motivation Improved sleep quality These are indirect but meaningful contributors to weight management