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To summarize, B-Complex supplements combine a number of B Vitamins into a convenient package to support cellular metabolism, brain and nervous system health, and whole-body wellness

Vitamin B-12-deficiency affects immunoglobulin production and cytokine levels in mice
Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur

They found that close to 37% suffered from a marginal deficiency of B12 whereas 14% had severe deficiency
