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It also showed a sustained IOP-lowering effect reaching the normal IOP level in the first 3h and sustained over 7 days

Within these dimers, signaling of the protomers involved are modified through facilitation, inhibition, and even modification of signaling pathways resulting in physiological consequences not seen in the absence of these dimers

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These mutants were also more susceptible than WT to another ITC, sulforaphane
