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doi: 10.2147/IJN.S352538
In particular, TLR4 recognizes LPS derived from CST IV-associated bacteria via the CD14-MD-2 complex, thereby activating MyD88-dependent pathways to trigger NF-B signaling 57,58
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The Nrf2 pathway is primarily responsible for mediating antioxidant defenses, whereas the NF-B and MAPK pathways play roles in proinflammatory and stress-related responses
