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PMID 28485121

In neurons, Grx has a protective effect on redox-sensitive enzymes and ion channels, meaning that its dysfunction is implicated in several neurodegenerative disorders involving protein misfolding and redox signaling dysregulation (Ogata et al., 2021)

The emergence of impaired glucose tolerance in HFD-fed mice indicated the successful establishment of the diabetes model (Supplementary information, Fig

Available online at: (Accessed November 12, 2025)

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Mitochondrial dysfunction is defined as diminished mitochondrial biogenesis, altered membrane potential, and the decrease in mitochondrial number and altered activities of oxidative proteins due to the accumulation of ROS in cells and tissues [89]