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These and other data discussed above suggest that the overall redox state of the cell influences whether excess GPx-1 is pro- or antisurvival

Patients experiencing persistent gastrointestinal adverse effects may benefit from slower titration schedules or maintaining lower doses for longer periods before attempting escalation

Supplementation of dietary glutamate to healthy weaning piglets led to an increase in overall intestinal health, as evidenced by higher villus height and enhanced intestinal mucosal thickness and integrity (122, 134)