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60 Additionally, a decrease in the activity of SOD and GPx has been reported in patients with various types of cancer, and this reduction has been implicated in an increased risk of cancer and poor prognosis

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Because the Pentose Phosphate Pathway is so slow and restricted by the lack of G-6-PDH, the cells cannot push glucose through the pathway fast enough to manufacture new D-ribose

First, tissues must increase the fraction of energy they derive from fat