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iHLOs model for toxicology applications To evaluate iHLOs as a model for toxicology studies, we compared proteomic profiles of Day 30 iHLOs, PHHs, HepG2 cells, and HepaRG cells against human liver tissue

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SLC25A39 as well as mitochondrial GSH may also represent promising drug targets for cancer, since manipulating SLC25A39 functioning or mitochondrial GSH in tumor cells may induce selective oxidative stress, leading to cell death

There is evidence that mechanosensitivity is not limited to the classic intrinsic sensory neuron, but is a property of a broader population of enteric neurons [63]