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2) Stress Management Chronic stress can cause glucocorticoid resistance

Lopez-Oliva, J.Y
Mubashir Hassan et al

Glutathione has been proved to improve strength and endurance, as well as decrease muscle damage and recovery time

Cell 16 , 550561 (2005)
The first stage is Trem2-independent and involves a reduction in homeostatic microglia checkpoint genes such as Cx3cr1, P2ry12 , and P2ry13 , along with upregulation of genes including the Trem2-signaling adaptor Tyrobp, Apoe , and B2m