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treated 6 patients with single large-scale mtDNA deletion syndromes using hematopoietic cells enriched with exogenous mitochondria, demonstrating clinical improvements [187]

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Thiomethyl shunt A series of reactions in which sulfur is added to an electrophile via the cysteine S -conjugate -lyase pathway followed by an enzyme-catalyzed S -methylation reaction with S -adenosyl-l-methionine as methyl donor

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