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doi: 10.1016/j.ijbiomac.2021.11.201 62 ZhangYZhuMPanJQiuQTongXHuXet al

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Lactate, histone lactylation and cancer hallmarks

A 20-week pilot trial examined the safety and tolerability of increasing dosages of coenzyme Q 10 (1,200 mg/day, 2,400 mg/day, and 3,600 mg/day) in eight healthy subjects and in 20 patients with Huntingtons disease

This study demonstrated that ALA can provide supportive therapy in cancer and may represent a promising adjuvant therapy to attenuate paclitaxel-induced peripheral neuropathy and counteract doxorubicin-induced cardiotoxicity