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Scientists first became interested in this compound because they found it protects the stomach and gut

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[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Cheon S., Culver A.M., Bagnell A.M., Ritchie F.D., Vacharasin J.M., McCord M.M., Papendorp C.M., Chukwurah E., Smith A.J., Cowen M.H., et al

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Besides, tumor-associated macrophage membranes (TAMMs) derived from primary tumors can block the interaction between TAMs and cancer cells by depleting CSF1 secreted by tumor cells in the TME, such as NPR@TAMM nanoparticle-mediated photodynamic immunotherapy formed by TAMM coated with conjugated photosensitizers can convert macrophages from an immunosuppressed M2-like phenotype to a more inflammatory M1-like phenotype thereby improving the anti-tumor immune response (67)