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In conclusion, clinical trials for SCA3 have been sparse and underwhelming in terms of their power to detect change, yet there are several advances and opportunities that should allow for a sorely needed increase in the number of interventional studies that can be performed

As a potent inhibitor of both COX-2 and 5-LOX, compound 5 also suppressed M1 microglial phenotype polarization

Dynamic bloodbrain barrier regulation in mild traumatic brain injury