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And while its true that a B12 deficiency can contribute to those things, there is one problem, says Ashley Barrient, a clinical dietitian at the Loyola Center for Metabolic Surgery & Bariatric Care in Chicago: Most of us arent deficient

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Controlled freezing studies of recombinant hGH demonstrated that insoluble particulate aggregation increases sharply with cooling rate, with pH 7.4 formulations producing markedly more light-scattering particulates than pH 7.8 formulations after freeze-thaw (Eckhardt, Oeswein & Bewley, 1991)

Store in a cool, dark, and dry place, preferably in the refrigerator, and keep it away from sunlight to maintain quality and integrity.