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found methylation in the hMLH1 promoter region in peripheral blood lymphocytes in 4 of 30 patients with juvenile-onset sporadic colon cancer or multiple cancer, and one of the four patients had multiple cancer, including endometrial cancer [34]

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It also modulates HDAC activity, enhancing the expression of proapoptotic genes and suppressing epithelialmesenchymal transition (EMT), a key step in metastasis

In the past, when AX was extracted from lobsters by Kuhn and Srensen, it was considered optically inactive since it displayed minimal optical rotation [11]
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