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However, a widening of the ring system was productive and the Ang IV analogue 21 with a 13-membered macrocycle exhibited a moderate IRAP inhibitory capacity

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In vivo efficacy studies In the pilot study, HCT116 cells (1 10 6 ) in exponential phase were injected subcutaneouslyinto the left flank of 8- to 10-week-old female nude mice (2530 g

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Lancet 1 , 783784 (1981)

35: 16579 Grossman S, Budinsky R, Jollow D
