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Genetic polymorphisms associated with reactive oxygen species and blood pressure regulation

It is widely considered one of the most powerful antioxidants on the planet, with studies showing it is significantly more effective at neutralising free radicals than standard Vitamin E

J Cardiovasc Pharm 2022;79:e75e86

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As noted earlier, the citrate synthase reaction that condenses oxaloacetate with acetyl-CoA has a standard free energy of about 8 kcal/mol and is responsible for pulling the MDH reaction in the forward direction