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In the seven-day week before treatment begins, patients will receive: At least five daily doses of folic acid One intramuscular injection of vitamin B12 A corticosteroid (dexamethasone) the day before, the day of and the day after treatment These supplements help reduce the incidence of side effects for patients

The accumulation factor (equation [7]) assumes that the drug follows a one-compartment model ( Figure 32 B), and the peak concentration prediction assumes that the absorption rate is much faster than the elimination rate

Additionally, in 2017, Carloni et al

E., Archer, C